SCHEMBL651122

SCHEMBL651122

BrC(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KCNN4 O15554 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TRPA1 O75762 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ALOX15 P16050 1/20 0.35
PTPN1 P18031 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10590017 0.79 ALDH1A1 (0.41) ALDH1A1KCNN4TSHRMAPK1TDP1
SCHEMBL6050021 0.77 KCNN4 (0.46) ALDH1A1KCNN4TSHRMAPK1TDP1
SCHEMBL5650092 0.77 KIF11 (0.39) ALDH1A1KCNN4TSHRMAPK1CYP1A2
SCHEMBL4812454 0.76 KCNN4 (0.35) ALDH1A1KCNN4TSHRMAPK1TRPA1
SCHEMBL4815486 0.75 KCNN4 (0.33) ALDH1A1KCNN4TSHRMAPK1CYP1A2
SCHEMBL2860719 0.75 CYP1A2 (0.39) ALDH1A1KCNN4TSHRMAPK1CYP1A2
SCHEMBL9162573 0.75 TSHR (0.43) ALDH1A1KCNN4TSHRMAPK1CES2
SCHEMBL28818191 0.75 MAPK1 (0.44) ALDH1A1KCNN4TSHRMAPK1TAAR1
SCHEMBL4811564 0.71 KCNN4 (0.35) ALDH1A1KCNN4TSHRMAPK1
SCHEMBL17931025 0.71 TSHR (0.39) ALDH1A1KCNN4TSHRMAPK1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US claimed
US-20100029828-A1 Brominated Diphenyl Ethane Mixtures and Resin Compositions Including the Same CHEIL INDUSTRIES INC. (KR) 2010-02-04 US claimed
US-8334332-B2 Flame-retardant thermoplastic resin composition with excellent color tone CHEIL INDUSTRIES INC. (KR) 2012-12-18 US disclosed
US-8193272-B2 Flame-retardant high impact vinyl aromatic resin composition having good fluidity CHEIL INDUSTRIES INC. (KR) 2012-06-05 US disclosed
US-8119812-B2 Thiazolidinone derivative SBI BIOTECH CO., LTD. (JP) 2012-02-21 US disclosed
US-8119720-B2 Thermoplastic resin composition having improved flowability CHEIL INDUSTRIES INC. (KR) 2012-02-21 US disclosed
US-20110190299-A1 THIAZOLIDINONE DERIVATIVE SBI BIOTECH CO., LTD. (JP) 2011-08-04 US disclosed
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US disclosed
US-20110160343-A1 Flame-Retardant Thermoplastic Resin Composition with Excellent Color Tone CHEIL INDUSTRIES INC. (KR) 2011-06-30 US disclosed
US-20100168292-A1 Thermoplastic Resin Composition Having Improved Flowability CHEIL INDUSTRIES INC. (KR) 2010-07-01 US disclosed
US-20100152342-A1 Flame-Retardant High Impact Vinyl Aromatic Resin Composition Having Good Fluidity CHEIL INDUSTRIES INC. (KR) 2010-06-17 US disclosed
US-20100029828-A1 Brominated Diphenyl Ethane Mixtures and Resin Compositions Including the Same CHEIL INDUSTRIES INC. (KR) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190299-A1 THIAZOLIDINONE DERIVATIVE CDC7, CDK17, CDCA2 ALDH1A1 2165/4885KCNN4 4440/4885TSHR 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.