SCHEMBL5069137

SCHEMBL5069137

Cc1ccc(O)c(-c2nc(N)nc(N)n2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.68
SMN1; SMN2 Q16637 4/20 0.56
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 3/20 0.53
RAB9A P51151 3/20 0.49
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 1/20 0.48
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
CDK9 P50750 3/20 0.48
KDM4E B2RXH2 2/20 0.48
LMNA P02545 2/20 0.48
CASP3 P42574 2/20 0.48
SENP7 Q9BQF6 2/20 0.48
NFKB1 P19838 1/20 0.48
CDK5 Q00535 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
CDK5R1 Q15078 1/20 0.48
SENP8 Q96LD8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12714307 0.86 TRPA1 (0.52) NPC1TDP1ALDH1A1RAB9AALOX15
SCHEMBL9566561 0.81 RAB9A (0.52) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A
SCHEMBL6511484 0.81 ALDH1A1 (0.47) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A
SCHEMBL17866357 0.78 NPC1 (1.00) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A
SCHEMBL9566466 0.78 HTR2B (0.68) NPC1SMN1; SMN2RAB9APDCD1CD274
SCHEMBL2489752 0.78 NPC1 (0.68) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A
SCHEMBL125550 0.77 RAB9A (0.52) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A
SCHEMBL9444924 0.76 IDO1 (0.44) NPC1TDP1ALDH1A1RAB9AALOX15
SCHEMBL9444864 0.75 NPC1 (0.47) NPC1TDP1ALDH1A1RAB9AALOX15
SCHEMBL9487748 0.75 CYP1A2 (0.58) NPC1SMN1; SMN2TDP1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1193513-B1 Method of producing color filter DAINIPPON INK & CHEMICALS (JP) 2008-12-03 EP disclosed
US-6929827-B2 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-08-16 US disclosed
CN-1188715-C Method for producing color filter DAINIPPON INK & CHEMICALS (JP) 2005-02-09 CN disclosed
US-20020081376-A1 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-06-27 US disclosed
CN-1346989-A Method for producing color filter DAINIPPON INK & CHEMICALS (JP) 2002-05-01 CN disclosed
EP-1193513-A2 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-04-03 EP disclosed