Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.33 |
| ▸ | MME | P08473 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650395 | 0.86 | MEN1 (0.35) | MEN1KMT2AAGTR1MMEAGTR2 | |
| SCHEMBL651421 | 0.85 | AGTR1 (0.41) | AGTR1MMEAGTR2 | |
| SCHEMBL650483 | 0.81 | AGTR1 (0.35) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL648737 | 0.76 | TSHR (0.37) | AGTR1AGTR2 | |
| SCHEMBL652416 | 0.75 | ADRA1D (0.37) | AGTR1CNR2 | |
| SCHEMBL650210 | 0.74 | CNR2 (0.33) | CNR2CNR1 | |
| SCHEMBL650385 | 0.72 | ADORA3 (0.36) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL652197 | 0.71 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL651121 | 0.71 | MEN1 (0.34) | MEN1KMT2AAGTR1 | |
| SCHEMBL5929232 | 0.71 | PARP1 (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |