SCHEMBL6512425

SCHEMBL6512425

C=C(C)[Si](OCCCCCC)(OCCCCCC)OCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
CES2 O00748 1/20 0.41
THRB P10828 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
LPAR3 Q9UBY5 6/20 0.38
LPAR2 Q9HBW0 5/20 0.38
LPAR1 Q92633 2/20 0.38
NAAA Q02083 1/20 0.38
RECQL P46063 2/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
EPHX2 P34913 1/20 0.36
BLM P54132 1/20 0.36
GBA1 P04062 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513370 1.00 TSHR (0.47) TSHRCES2THRBMEN1HTT
SCHEMBL7775320 1.00 TSHR (0.47) TSHRCES2THRBMEN1HTT
SCHEMBL6509487 1.00 TSHR (0.47) TSHRCES2THRBMEN1HTT
SCHEMBL959989 0.91 ALDH1A1 (0.39) TSHRCES2HPGD
SCHEMBL25191483 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT
SCHEMBL1157411 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT
SCHEMBL29010387 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT
SCHEMBL10438599 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT
SCHEMBL8955296 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT
SCHEMBL28413946 0.72 THRB (0.44) TSHRCES2THRBMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124747-A1 Coating composition for ink-jet recording medium and ink-jet recording medium DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2005-06-09 US disclosed
EP-1470928-A1 COATING COMPOSITION FOR INK-JET RECORDING MEDIUM AND INK-JET RECORDING MEDIUM Clariant International Ltd. (CH) 2004-10-27 EP disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0989168-A1 Water-based coating composition Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed