Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.48 |
| ▸ | AURKA | O14965 | 5/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605428 | 0.83 | HRH4 (0.61) | LMNAUSP2TSHRHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL6512235 | 0.82 | HRH3 (0.63) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL6510066 | 0.82 | LMNA (0.53) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL3196818 | 0.79 | LMNA (0.56) | LMNAHRH4HRH3KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6508476 | 0.79 | LMNA (0.65) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL6510068 | 0.78 | HRH4 (0.55) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL3997222 | 0.78 | HRH4 (0.64) | HRH4HRH3 | |
| SCHEMBL3210909 | 0.77 | HRH4 (0.62) | HRH4HRH3 | |
| SCHEMBL10567412 | 0.76 | HRH4 (0.85) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL6023051 | 0.76 | USP2 (0.52) | LMNAUSP2TSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054239-A1 | 2-AMINOPYRIMIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2005-06-16 | — | — | WO | disclosed |