Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023051 | 0.91 | USP2 (0.52) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL6512558 | 0.82 | LMNA (0.56) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL1773837 | 0.81 | LMNA (0.50) | LMNAHTTHRH4CYP1A2MAPT | |
| SCHEMBL6023488 | 0.80 | ADORA2A (0.45) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL3214623 | 0.78 | HRH4 (0.58) | HRH4 | |
| SCHEMBL4001768 | 0.77 | HRH4 (0.46) | HRH4 | |
| SCHEMBL1775871 | 0.77 | HRH4 (0.57) | HRH4VCP | |
| SCHEMBL18601604 | 0.76 | HRH4 (0.53) | HRH4 | |
| Hydrochloric Acid SCHEMBL6508476 | 0.76 | LMNA (0.65) | LMNAUSP2TSHRHTTHSD17B10 | |
| SCHEMBL6510068 | 0.75 | HRH4 (0.55) | LMNAUSP2TSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054239-A1 | 2-AMINOPYRIMIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2005-06-16 | — | — | WO | disclosed |