Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509745 | 0.85 | MAPK1 (0.53) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6510506 | 0.81 | MAPK1 (0.56) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6510602 | 0.80 | MAPK1 (0.63) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6510249 | 0.80 | MAPK1 (0.62) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6508660 | 0.80 | MAPK1 (0.52) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL5923256 | 0.79 | MAPK1 (0.56) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL10498921 | 0.77 | LMNA (0.61) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL10498925 | 0.77 | LMNA (0.61) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL6510588 | 0.77 | LMNA (0.50) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4981988 | 0.77 | MAPK1 (0.69) | MAPK1MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |