Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513286 | 0.85 | MAPK1 (0.62) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL5923121 | 0.80 | MAPK1 (0.48) | MAPK1F9F10SIRT2ALOX5 | |
| SCHEMBL6510506 | 0.74 | MAPK1 (0.56) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL6510602 | 0.73 | MAPK1 (0.63) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL14861786 | 0.73 | SIGMAR1 (0.65) | MEN1RAB9AKMT2ALMNAADORA2A | |
| SCHEMBL6508660 | 0.73 | MAPK1 (0.52) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL6510249 | 0.73 | MAPK1 (0.62) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL4109150 | 0.72 | SIGMAR1 (0.61) | MAPK1RAB9AKMT2ALMNAADORA2A | |
| SCHEMBL6510588 | 0.72 | LMNA (0.50) | MAPK1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL10498921 | 0.71 | LMNA (0.61) | MEN1RAB9AKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |