SCHEMBL6513538

SCHEMBL6513538

N#Cc1cc(C#N)c(S)c(C#N)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 4/20 0.39
VCAM1 P19320 2/20 0.39
TTR P02766 2/20 0.37
ALB P02768 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 1/20 0.33
IMPDH2 P12268 1/20 0.31
IMPDH1 P20839 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514504 0.97 TRPV4 (0.38) TRPV4VCAM1TTRALBMEN1
SCHEMBL6513668 0.97 TRPV4 (0.38) TRPV4VCAM1TTRALBMEN1
SCHEMBL22958414 0.84 TSHR (0.37) TRPV4VCAM1TTRALBMEN1
SCHEMBL17997019 0.82 CA2 (0.34) TRPV4TSHRIMPDH2IMPDH1ALDH1A1
SCHEMBL22780686 0.76 TRPV4 (0.38) TRPV4KMT2ATSHRALDH1A1CYP2A6
SCHEMBL2040623 0.74 VCAM1 (0.41) TRPV4VCAM1TTRALBMEN1
SCHEMBL3048555 0.74 VCAM1 (0.41) TRPV4VCAM1TTRALBMEN1
SCHEMBL21918828 0.72 VCAM1 (0.39) TRPV4VCAM1TTRALBMEN1
SCHEMBL22130481 0.72 TTR (0.48) TRPV4VCAM1TTRALBMEN1
SCHEMBL17546133 0.72 TRPV4 (0.39) TRPV4VCAM1TTRALBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365397-B1 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER IND & SANTE (FR) 1994-09-28 EP claimed
EP-0365397-A2 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1990-04-25 EP claimed
EP-3604321-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-02-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
EP-0365397-B1 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER IND & SANTE (FR) 1994-09-28 EP disclosed
US-5246961-A Venous antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1993-09-21 US disclosed
US-5101048-A Antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1992-03-31 US disclosed
EP-0365397-A2 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1990-04-25 EP disclosed