SCHEMBL6514504

SCHEMBL6514504

N#Cc1cc(C#N)c(S)c(C#N)c1.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 4/20 0.38
VCAM1 P19320 2/20 0.38
TTR P02766 2/20 0.36
ALB P02768 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.32
IMPDH2 P12268 1/20 0.30
IMPDH1 P20839 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513538 0.97 TRPV4 (0.39) TRPV4VCAM1TTRALBMEN1
SCHEMBL6513668 0.95 TRPV4 (0.38) TRPV4VCAM1TTRALBMEN1
SCHEMBL17997019 0.84 CA2 (0.34) TRPV4TSHRIMPDH2IMPDH1
SCHEMBL22958414 0.81 TSHR (0.37) TRPV4VCAM1TTRALBMEN1
SCHEMBL22780686 0.74 TRPV4 (0.38) TRPV4KMT2ATSHR
SCHEMBL2040623 0.72 VCAM1 (0.41) TRPV4VCAM1TTRALBMEN1
SCHEMBL3048555 0.72 VCAM1 (0.41) TRPV4VCAM1TTRALBMEN1
SCHEMBL22130481 0.70 TTR (0.48) TRPV4VCAM1TTRALBMEN1
SCHEMBL21918828 0.70 VCAM1 (0.39) TRPV4VCAM1TTRALBMEN1
SCHEMBL17546133 0.70 TRPV4 (0.39) TRPV4VCAM1TTRALBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
CN-105381573-B Golf 邓禄普体育用品株式会社 2018-03-09 CN disclosed
US-20180036602-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-02-08 US disclosed
CN-103446724-B Golf 邓禄普体育用品株式会社 2018-01-19 CN disclosed
US-20170361169-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2017-12-21 US disclosed
US-20170304684-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2017-10-26 US disclosed
EP-2669327-B1 Golf ball DUNLOP SPORTS CO LTD (JP) 2017-10-04 EP disclosed
EP-2669328-B1 Golf ball DUNLOP SPORTS CO LTD (JP) 2017-03-22 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed