Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.55 |
| ▸ | CYCS | P99999 | 3/20 | 0.54 |
| ▸ | TERT | O14746 | 4/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777544 | 1.00 | TOP1 (0.55) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28494122 | 0.98 | TOP1 (0.54) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL29437849 | 0.98 | TOP1 (0.54) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28508880 | 0.98 | TOP1 (0.54) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28346165 | 0.98 | TOP1 (0.54) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28474117 | 0.98 | TOP1 (0.54) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28759678 | 0.94 | TOP1 (0.54) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL10075062 | 0.89 | ABCG2 (0.47) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL29683952 | 0.83 | TOP1 (0.55) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL1674104 | 0.83 | TOP1 (0.55) | TOP1CYCSTERTENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12546743-B2 | Electrochemical sensor and related methods | UNIVERSITY OF SOUTH FLORIDA (US) | 2026-02-10 | — | — | US | disclosed |
| US-20230296554-A1 | ELECTROCHEMICAL SENSOR AND RELATED METHODS | UNIVERSITY OF SOUTH FLORIDA | 2023-09-21 | — | — | US | disclosed |
| EP-0831891-B1 | OXIDANT SCAVENGERS | UNIV DUKE (US) | 2005-10-19 | — | — | EP | disclosed |
| US-20040019031-A1 | Oxidant scavengers | DUKE UNIVERSITY | 2004-01-29 | — | — | US | disclosed |
| US-6127356-A | MODULATING INTRA- OR EXTRACELLULAR LEVELS OF OXIDANTS SUCH AS SUPEROXIDE RADICALS, HYDROGEN PEROXIDE AND PEROXYNITRITES BY USING LOW MOLECULAR WEIGHT MIMETICS OF SUPEROXIDE DISMUTASE, CATALASE OR PEROXIDASE | DUKE UNIVERSITY (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1996040223-A1 | OXIDANT SCAVENGERS | DUKE UNIVERSITY (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12546743-B2 | Electrochemical sensor and related methods | EPX, MUC1, EPCAM | TOP1 4862/4885CYCS 2095/4885TERT 3462/4885 |
| US-20040019031-A1 | Oxidant scavengers | GPX4, LPO, PRDX5 | TOP1 4713/4885CYCS 232/4885TERT 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.