SCHEMBL6514388

SCHEMBL6514388

[C]1=CCC(=Cc2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HTT P42858 1/20 0.35
CYP1A2 P05177 2/20 0.34
F3 P13726 1/20 0.32
PIM1 P11309 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28066368 0.69 CYP1A2 (0.44) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL6745371 0.68 ALDH1A1 (0.37) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL28175288 0.65 CYP1A2 (0.34) ALDH1A1HTTCYP1A2F3PIM1
Methylamine SCHEMBL28226585 0.65 ALDH1A1 (0.35) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL11294752 0.63 CYP1A2 (0.43) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL11399507 0.61 CYP1A2 (0.42) ALDH1A1HTTCYP1A2F3HPGD
SCHEMBL22471741 0.61 CYP1A2 (0.34) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL8401484 0.60 CYP1A2 (0.33) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL8401481 0.60 CYP1A2 (0.33) ALDH1A1HTTCYP1A2F3PIM1
SCHEMBL29179077 0.60 PARP1 (0.39) ALDH1A1HTTCYP1A2F3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855950-B2 Method for conductance switching in molecular electronic junctions THE OHIO STATE UNIVERSITY (US) 2005-02-15 US disclosed
US-20040007758-A1 Method for conductance switching in molecular electronic junctions THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION 2004-01-15 US disclosed
WO-2003081638-A2 METHOD FOR CONDUCTANCE SWITCHING IN MOLECULAR ELECTRONIC JUNCTIONS THE OHIO STATE UNIVERSITY (US) 2003-10-02 WO disclosed