Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036699 | 0.87 | KDM4E (0.66) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL6514641 | 0.85 | MEN1 (0.43) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1685962 | 0.83 | ALDH1A1 (0.65) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL12009978 | 0.79 | ALDH1A1 (0.56) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL24054706 | 0.76 | KDM4E (0.52) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL10044899 | 0.74 | ALDH1A1 (0.53) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL15936261 | 0.73 | MEN1 (0.51) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL16102514 | 0.73 | MEN1 (0.39) | KDM4ELMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10044903 | 0.73 | ALDH1A1 (0.51) | KDM4ELMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL3761069 | 0.73 | ALDH1A1 (0.51) | KDM4ELMNAALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| CN-100376572-C | Anti-infective agents | ABBOTT LAB (US) | 2008-03-26 | — | — | CN | disclosed |
| CN-1735612-A | Anti-infective agents | ABBOTT LAB (US) | 2006-02-15 | — | — | CN | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885LMNA 3232/4885ALDH1A1 1434/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885LMNA 3232/4885ALDH1A1 1434/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | KDM4E 4075/4885LMNA 4000/4885ALDH1A1 891/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885LMNA 3232/4885ALDH1A1 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.