Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424037 | 0.88 | SMN1; SMN2 (0.61) | ATML3MBTL1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL1848481 | 0.88 | SMN1; SMN2 (0.61) | ATML3MBTL1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL4853220 | 0.88 | SMN1; SMN2 (0.61) | ATML3MBTL1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL6472595 | 0.85 | ADRB2 (0.50) | ATML3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL323957 | 0.83 | ADRB2 (0.56) | ATML3MBTL1ADRB2SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL6473470 | 0.83 | ADRB2 (0.52) | ATML3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL323594 | 0.78 | BCHE (0.55) | ATMCYP1A2CYP2C19MAPTNPSR1 | |
| SCHEMBL22557446 | 0.78 | ADRB2 (0.50) | ATML3MBTL1CYP1A2CYP2C19ADRB2 | |
| SCHEMBL28295645 | 0.78 | ATM (0.58) | ATML3MBTL1AKT1CYP1A2CYP2D6 | |
| SCHEMBL8091287 | 0.77 | L3MBTL1 (0.57) | ATML3MBTL1AKT1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608630-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | Mitsubishi Pharma Corporation (JP) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |