SCHEMBL651489

SCHEMBL651489

CC(C)(NC(=O)c1cc2[nH]nc(NC(=O)c3ccccc3NC(=O)c3cccs3)c2o1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.47
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
TSHR P16473 2/20 0.43
FGFR4 P22455 1/20 0.42
AURKA O14965 1/20 0.42
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
STK33 Q9BYT3 1/20 0.38
MAPK1 P28482 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PKM P14618 1/20 0.38
APLNR P35414 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13850061 0.94 AURKA (0.46) RXFP1KMT2AMEN1MAPTTSHR
SCHEMBL2905881 0.88 RXFP1 (0.44) RXFP1KMT2AMEN1MAPTTSHR
SCHEMBL652230 0.88 RXFP1 (0.42) RXFP1KMT2AMEN1FGFR4AURKA
SCHEMBL2913843 0.86 KMT2A (0.48) RXFP1KMT2AMEN1MAPTTSHR
SCHEMBL4088416 0.86 LMNA (0.42) KMT2AMEN1MAPTAURKANPC1
SCHEMBL653327 0.85 AURKA (0.40) RXFP1FGFR4AURKAMAPK1
SCHEMBL651124 0.85 AURKA (0.40) RXFP1FGFR4AURKAALDH1A1
SCHEMBL653328 0.85 AURKA (0.38) RXFP1KMT2AMEN1FGFR4AURKA
SCHEMBL4082088 0.84 SMN1; SMN2 (0.41) RXFP1KMT2AMEN1MAPTTSHR
SCHEMBL4083197 0.84 SMN1; SMN2 (0.41) RXFP1KMT2AMEN1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111830816-B Self-adaptive timing method and device 南京天朗防务科技有限公司 2023-05-12 CN claimed
CN-114440856-A Method and device for constructing semantic map 北京地平线信息技术有限公司 2022-05-06 CN claimed
CN-113028586-A Control protection method and system for compressor 四川虹美智能科技有限公司 2021-06-25 CN claimed
CN-111784917-B Intelligent commodity vending machine based on self-learning algorithm 广州技诺智能设备有限公司 2021-04-02 CN claimed
CN-111161545-B Intersection region traffic parameter statistical method based on video 北京工业大学 2021-01-05 CN claimed
CN-111784917-A Intelligent commodity vending machine based on self-learning algorithm 广州技诺智能设备有限公司 2020-10-16 CN claimed
CN-107046465-B Intrusion-tolerant cloud storage data auditing method 安徽大学 2020-07-17 CN claimed
CN-111161545-A Intersection region traffic parameter statistical method based on video 北京工业大学 2020-05-15 CN claimed
CN-106816008-B A kind of congestion in road early warning and congestion form time forecasting methods 银江股份有限公司 2019-08-23 CN claimed
EP-3382911-A1 METHODS AND APPARATUS FOR TRANSMITTING AND RECEIVING BURST DATA Nokia Solutions and Networks Oy (FI) 2018-10-03 EP claimed
CN-105028296-A Special transport box device for liquefied natural gas fishing boat UNIV QINGDAO 2015-11-11 CN claimed
WO-2015043278-A1 METHOD AND SYSTEM FOR SIMULTANEOUSLY PERFORMING TARGET GENE HAPLOTYPE ANALYSIS AND CHROMOSOMAL ANEUPLOIDY DETECTION 深圳华大基因科技有限公司 2015-04-02 WO claimed
EP-1740506-B1 CONTROL OF COOLING WATER SYSTEM USING RATE OF CONSUMPTION OF FLUORESCENT POLYMER NALCO CO (US) 2012-02-29 EP claimed
US-8119641-B2 1H-furo[3,2-C]pyrazole compounds useful as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2012-02-21 US claimed
CN-100513331-C Control of cooling water system using rate of consumption of fluorescent polymer NALCO CO (US) 2009-07-15 CN claimed
EP-1805402-A1 ARRANGEMENT AND METHOD FOR CONTROLLING A COMBUSTION ENGINE Scania CV AB (PUBL) (SE) 2007-07-11 EP claimed
CN-1950304-A Control of cooling water system using rate of consumption of fluorescent polymer NALCO CO (US) 2007-04-18 CN claimed
US-7179384-B2 Control of cooling water system using rate of consumption of fluorescent polymer NALCO COMPANY (US) 2007-02-20 US claimed
WO-2006043875-A1 ARRANGEMENT AND METHOD FOR CONTROLLING A COMBUSTION ENGINE SCANIA CV AB (PUBL) (SE) 2006-04-27 WO claimed
US-20050242042-A1 Control of cooling water system using rate of consumption of fluorescent polymer ECOLAB USA INC. 2005-11-03 US claimed