Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757192 | 0.86 | KDM4E (0.42) | CYP1A2ALDH1A1ALOX15HTTUSP2 | |
| SCHEMBL6753935 | 0.80 | SCN10A (0.38) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL6516334 | 0.75 | CYP1A2 (0.47) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL22349154 | 0.74 | KDM4E (0.43) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| SCHEMBL353027 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AUSP2HPGD | |
| SCHEMBL6519944 | 0.73 | CYP1A2 (0.46) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL6517964 | 0.73 | CYP1A2 (0.46) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL18554461 | 0.72 | CYP1A2 (0.45) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL20378138 | 0.72 | CYP1A2 (0.45) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL6756157 | 0.71 | KDM4E (0.48) | KMT2AUSP2HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | AGOURON PHARMACEUTICALS, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | CHEK1, CHEK2, RAD1 | CYP1A2 3569/4885ALDH1A1 2713/4885ALOX15 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.