Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554461 | 0.84 | CYP1A2 (0.45) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL20378138 | 0.84 | CYP1A2 (0.45) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL6515025 | 0.75 | CYP1A2 (0.53) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL3421751 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTHCAR1GAA | |
| SCHEMBL1625968 | 0.72 | HCAR1 (0.33) | HCAR1 | |
| SCHEMBL6519944 | 0.72 | CYP1A2 (0.46) | CYP1A2ALDH1A1ALOX15HTTMEN1 | |
| SCHEMBL7045409 | 0.72 | KDM4E (0.44) | ALDH1A1HTTHPGDHCAR1GAA | |
| SCHEMBL13542739 | 0.71 | KDM4E (0.40) | CYP1A2ALDH1A1HTTUSP2HPGD | |
| SCHEMBL6512270 | 0.70 | GRM5 (0.46) | ALDH1A1ALOX15HTTMEN1KMT2A | |
| SCHEMBL6512272 | 0.70 | GRM5 (0.46) | ALDH1A1ALOX15HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | AGOURON PHARMACEUTICALS, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | CHEK1, CHEK2, RAD1 | CYP1A2 3569/4885ALDH1A1 2713/4885ALOX15 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.