Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518970 | 0.91 | HCAR2 (0.61) | HCAR2ATMMAPTALDH1A1LMNA | |
| SCHEMBL27806191 | 0.91 | HCAR2 (0.61) | HCAR2ATMMAPTALDH1A1LMNA | |
| SCHEMBL2627702 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL18288662 | 0.89 | PKM (0.41) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL10024386 | 0.87 | GSTP1 (0.39) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL6524294 | 0.85 | ATM (0.45) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL10947716 | 0.81 | — | — | |
| SCHEMBL9464814 | 0.80 | HCAR2 (0.40) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL27327529 | 0.80 | AKT1 (0.41) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL868205 | 0.79 | HCAR2 (0.43) | HCAR2ATMKEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707897-A | Process for preparing michelia lactone derivatives | 鄂尔多斯市尚德艾康药业有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-113966330-A | Crystalline form S4 of the PLK4 inhibitor (1R,2S) - (E) -2- (3- (4- ((cis-2, 6-dimethylmorpholine) methyl) styryl) -1H-imidazol-6-yl) -5 ' -methoxyspiro [ cyclopropane-l, 3 ' -indolin ] -2 ' -one fumarate | 大学健康网络 | 2022-01-21 | — | — | CN | disclosed |
| EP-3813835-A1 | SALTS OF (S)-(5-CYCLOBUTOXY-2-METHYL-6-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)-3,4-DIHYDROQUINOLIN-1(2H)-YL)(CYCLOPROPYL)METHANONE AND SOLID FORMS THEREOF | Forma Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-108349978-A | Solid forms and formulations of (S) -4- (8-amino-3- (1- (but-2-ynoyl) pyrrolidin-2-yl) imidazo [1,5-a ] pyrazin-1-yl) -N- (pyridin-2-yl) benzamide | 安塞塔制药公司 | 2018-07-31 | — | — | CN | disclosed |
| US-6958366-B2 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030118544-A1 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-06-26 | — | — | US | disclosed |
| CN-87106804-A | Imidazopyridine derivatives, the pharmaceutical compositions that contains imidazopyridine derivatives and their preparation method | — | 1988-05-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030118544-A1 | Antifouling coating composition and novel resin | COL1A1, GLRA1, COL2A1 | HCAR2 3143/4885ATM 4559/4885KEAP1 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.