Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510755 | 0.92 | MEP1B (0.56) | CALM1CAMKK2MEP1BPOLBMTNR1A | |
| SCHEMBL6512357 | 0.88 | TAS2R14 (0.43) | MEP1BPOLBMTNR1AMTNR1BMEN1 | |
| SCHEMBL6509273 | 0.87 | MEP1B (0.53) | CALM1CAMKK2MEP1BHSD17B2POLB | |
| SCHEMBL6512683 | 0.85 | MEP1B (0.46) | MEP1BFFAR1 | |
| SCHEMBL6511963 | 0.85 | MEP1B (0.47) | CALM1CAMKK2MEP1BHSD17B2POLB | |
| SCHEMBL6515065 | 0.84 | TSHR (0.55) | CALM1CAMKK2FFAR1 | |
| SCHEMBL6508483 | 0.83 | TSHR (0.45) | MEP1BKMT2AKDM4EALDH1A1FFAR1 | |
| SCHEMBL6513938 | 0.83 | PKM (0.44) | MEP1BMEN1KMT2AMAPTFFAR1 | |
| SCHEMBL6519088 | 0.83 | MEN1 (0.51) | MEP1BMEN1KMT2ABCHEACHE | |
| SCHEMBL6515110 | 0.83 | HPGD (0.47) | MEP1BPOLBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |