SCHEMBL6516017

SCHEMBL6516017

O=S(=O)(O)c1csc(-c2ccccc2)c1SSc1c(S(=O)(=O)O)csc1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.35
TSHR P16473 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
KDM4E B2RXH2 1/20 0.33
PTGS2 P35354 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PHGDH O43175 1/20 0.32
RCE1 Q9Y256 1/20 0.32
BACE1 P56817 1/20 0.32
RECQL P46063 1/20 0.31
MYC P01106 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515728 0.80 PTGS2 (0.33) SMN1; SMN2NPC1RAB9AMAPTHPGD
SCHEMBL27510482 0.72 BACE1 (0.44) SMN1; SMN2TSHRNPC1RAB9AMAPT
SCHEMBL6519379 0.70 BCAT2 (0.44) SMN1; SMN2NPC1RAB9AMAPTHPGD
SCHEMBL6516451 0.70 MAPT (0.47) SMN1; SMN2TSHRNPC1RAB9AMAPT
SCHEMBL3059985 0.66 HTR6 (0.45) SMN1; SMN2TSHRMAPTPTGS2ALDH1A1
Biphenyl SCHEMBL27380486 0.63 TSHR (0.43) SMN1; SMN2TSHRALDH1A1RCE1MYC
SCHEMBL6519153 0.63 NPC1 (0.31) SMN1; SMN2NPC1RAB9AMAPTHPGD
SCHEMBL232659 0.62 CASP1 (0.47) SMN1; SMN2TSHRHPGDPTGS2ALDH1A1
SCHEMBL29743050 0.62 CASP1 (0.47) SMN1; SMN2TSHRHPGDPTGS2ALDH1A1
Phosphine SCHEMBL27503675 0.62 PTGS2 (0.46) SMN1; SMN2TSHRNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed