SCHEMBL6516047

SCHEMBL6516047

CC(=O)c1ccc(SSc2ccc(C(C)=O)cc2C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
PKM P14618 1/20 0.44
HPGD P15428 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
MAPT P10636 6/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
HSD17B1 P14061 1/20 0.41
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PRKCI P41743 1/20 0.39
S100A4 P26447 1/20 0.39
KMT2A Q03164 1/20 0.39
PDE7A Q13946 1/20 0.39
POLB P06746 2/20 0.39
MAPK1 P28482 1/20 0.38
STAT3 P40763 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361232 0.86 TAS1R3 (0.57) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL11813389 0.81 TAS1R3 (0.45) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL10360994 0.81 PKM (0.43) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL6517213 0.79 PKM (0.48) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL13859381 0.78 ALDH1A1 (0.48) CYP2A6PKMHPGDLMNAMAPT
SCHEMBL29787835 0.78 SMN1; SMN2 (0.57) CYP2A6PKMHPGDLMNAMAPT
SCHEMBL110321 0.78 SMN1; SMN2 (0.57) CYP2A6PKMHPGDLMNAMAPT
SCHEMBL6519931 0.78 HPGD (0.42) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL6519272 0.78 PRKCI (0.55) CYP2A6PKMHPGDL3MBTL1LMNA
SCHEMBL6511211 0.76 AKR1C3 (0.51) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20130005507-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005505-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed