SCHEMBL6519931

SCHEMBL6519931

CC(=O)c1ccc(SSc2ccc(C(C)=O)cc2Cl)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.42
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 8/20 0.41
RAB9A P51151 5/20 0.41
NPC1 O15118 4/20 0.41
TSHR P16473 1/20 0.41
CYP2A6 P11509 1/20 0.40
PKM P14618 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B1 P14061 1/20 0.40
ESRRA P11474 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HTT P42858 1/20 0.38
NLRP1 Q9C000 1/20 0.38
PRKCI P41743 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4131936 0.86 ALDH1A1 (0.42) HPGDLMNAL3MBTL1MAPTRAB9A
SCHEMBL21899848 0.82 TSHR (0.63) HPGDL3MBTL1MAPTTSHRALDH1A1
SCHEMBL5830744 0.80 MAPT (0.48) HPGDLMNAL3MBTL1MAPTRAB9A
SCHEMBL313211 0.79 TSHR (0.64) HPGDMAPTRAB9ANPC1TSHR
SCHEMBL29655535 0.79 TSHR (0.64) HPGDMAPTRAB9ANPC1TSHR
SCHEMBL8478583 0.79 TSHR (0.64) HPGDMAPTRAB9ANPC1TSHR
SCHEMBL6517213 0.78 PKM (0.48) HPGDLMNAL3MBTL1MAPTRAB9A
SCHEMBL6516047 0.78 CYP2A6 (0.46) HPGDLMNAL3MBTL1MAPTRAB9A
SCHEMBL6515653 0.77 HPGD (0.39) HPGDLMNAL3MBTL1MAPTRAB9A
SCHEMBL28556474 0.77 MAPT (0.45) HPGDLMNAL3MBTL1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005505-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005507-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed