Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.33 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583178 | 1.00 | NFE2L2 (0.33) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL19540178 | 0.85 | FGF23 (0.36) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL1396860 | 0.85 | FGF23 (0.36) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL93457 | 0.81 | ALDH1A1 (0.39) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL29554163 | 0.81 | ALDH1A1 (0.39) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL782094 | 0.81 | FGF23 (0.44) | NFE2L2FGF23KDM4EALDH1A1MAPT | |
| SCHEMBL25447214 | 0.81 | FGF23 (0.33) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL12508936 | 0.81 | FGF23 (0.36) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL19596554 | 0.81 | FGF23 (0.33) | NFE2L2FGF23TRIM24TRIM33KDM4E | |
| SCHEMBL24601141 | 0.81 | FGF23 (0.33) | NFE2L2FGF23TRIM24TRIM33KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421623-A | Nanostructured, its manufacture method and its using method of biological conjugation | UNIV EMORY (US) | 2009-04-29 | — | — | CN | disclosed |
| EP-1546251-A2 | FUEL CELLS INCLUDING BIOCOMPATIBLE MEMBRANES AND METAL ANODES | Powerzyme, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004032306-A2 | FUEL CELLS INCLUDING BIOCOMPATIBLE MEMBRANES AND METAL ANODES | POWERZYME, INC. (US) | 2004-04-15 | — | — | WO | disclosed |