Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517249 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL6517247 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL907554 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL672248 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL14099603 | 0.72 | NOS1 (0.32) | CA1CA2CA4 | |
| SCHEMBL11591596 | 0.69 | CA1 (0.67) | CA1CA2CA4 | |
| SCHEMBL17063633 | 0.69 | CA1 (0.59) | CA1CA2CA4 | |
| SCHEMBL18813658 | 0.69 | L3MBTL1 (0.31) | — | |
| SCHEMBL3439389 | 0.67 | CA1 (0.32) | CA1CA2CA4 | |
| SCHEMBL3439393 | 0.67 | CA1 (0.32) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556019-A2 | COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS | Merz Pharma GmbH & Co. KGaA (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037234-A2 | COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2004-05-06 | — | — | WO | disclosed |