Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517249 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL6517246 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL6517247 | 1.00 | CA1 (0.42) | CA1CA2CA4 | |
| SCHEMBL672248 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL14099603 | 0.72 | NOS1 (0.32) | CA1CA2CA4 | |
| SCHEMBL11591596 | 0.69 | CA1 (0.67) | CA1CA2CA4 | |
| SCHEMBL17063633 | 0.69 | CA1 (0.59) | CA1CA2CA4 | |
| SCHEMBL18813658 | 0.69 | L3MBTL1 (0.31) | — | |
| SCHEMBL3439389 | 0.67 | CA1 (0.32) | CA1CA2CA4 | |
| SCHEMBL3439393 | 0.67 | CA1 (0.32) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682109-B1 | THE USE OF 1-AMINOCYCLOHEXANE DERIVATIVES TO MODIFY DEPOSITION OF FIBRILLOGENIC AS PEPTIDES IN AMYLOIDOPATHIES | MERZ PHARMA GMBH & CO KGAA (DE) | 2008-10-15 | — | — | EP | claimed |
| US-6602862-B1 | 1-Amino-alkylcyclohexanes as trypanocidal agents | MERZ PHARMA GMBH & CO., KGAA (DE) | 2003-08-05 | — | — | US | claimed |
| EP-2277850-A1 | 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists | Merz Pharma GmbH & Co. KGaA (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-1318800-B1 | 1-AMINO-ALKYLCYCLOHEXANES AS TRYPANOCIDAL AGENTS | MERZ PHARMA GMBH & CO KGAA (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6602862-B1 | 1-Amino-alkylcyclohexanes as trypanocidal agents | MERZ PHARMA GMBH & CO., KGAA (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-1303477-A2 | 1-AMINO-ALKYLCYCLOHEXANES AS 5-HT3- AND NEURONAL NICOTINICRECEPTOR ANTAGONISTS | MERZ + CO. GmbH & Co. (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001098253-A2 | 1-AMINO-ALKYLCYCLOHEXANES AS 5-HT3 AND NEURONAL NICOTINICRECEPTOR ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2001-12-27 | — | — | WO | disclosed |