Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223861 | 0.94 | CTSK (0.40) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9189498 | 0.85 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3401546 | 0.82 | ACACB (0.32) | CA1CA2 | |
| SCHEMBL1042116 | 0.81 | SMN1; SMN2 (0.36) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL4561830 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2145053 | 0.77 | MGAM (0.33) | ALDH1A1LMNA | |
| SCHEMBL126477 | 0.75 | CAD (0.39) | HTTL3MBTL1 | |
| SCHEMBL19549043 | 0.75 | ELANE (0.33) | CA2ALDH1A1 | |
| Methyl Alcohol SCHEMBL22551139 | 0.74 | CAD (0.38) | — | |
| SCHEMBL17261296 | 0.73 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412087-A | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-05-02 | — | — | US | claimed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-20050095652-A1 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-05-05 | — | — | US | disclosed |
| US-20050079529-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-04-14 | — | — | US | disclosed |
| US-20030108899-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2003-06-12 | — | — | US | disclosed |
| US-6506558-B1 | Deprotecting nucleoside, nucleotide or amino acid to form polypeptide or polynucleotide | AFFYMETRIX INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020137096-A1 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2002-09-26 | — | — | US | disclosed |
| US-6420169-B1 | Apparatus for forming polynucleotides or polypeptides | AFFYMETRIX, INC. | 2002-07-16 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| US-5412087-A | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-05-02 | — | — | US | disclosed |
| WO-1993022680-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF OLIGONUCLEOTIDES AND OTHER BIOLOGICAL POLYMERS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-11-11 | — | — | WO | disclosed |