Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517951 | 1.00 | MAPT (0.56) | MAPTCYP3A4TSHRADRA2AADRA2B | |
| SCHEMBL6508816 | 0.88 | MAPT (0.56) | MAPTCYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL14366560 | 0.81 | MAPT (0.58) | MAPTALDH1A1TDP1MAPK1NPC1 | |
| SCHEMBL2107414 | 0.79 | MAPT (0.56) | MAPTALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL2107416 | 0.79 | MAPT (0.56) | MAPTALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL1754834 | 0.79 | MAPT (0.56) | MAPTALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL973245 | 0.78 | MAPT (0.55) | MAPTTSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL973244 | 0.78 | MAPT (0.55) | MAPTTSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL2475726 | 0.78 | LMNA (0.50) | MAPTCYP3A4TSHRADRA2AADRA2B | |
| SCHEMBL3500948 | 0.78 | MAPT (0.55) | MAPTTSHRALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |
| WO-2002035580-A2 | THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES | MOLECULAR ELECTRONICS CORPORATION (US) | 2002-05-02 | — | — | WO | disclosed |