Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071036 | 0.86 | MAPT (0.54) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL2926204 | 0.83 | CES2 (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10894082 | 0.82 | TDP1 (0.61) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL702447 | 0.82 | TDP1 (0.61) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL9056471 | 0.81 | CES2 (0.66) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL16781991 | 0.80 | L3MBTL1 (0.71) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL4809206 | 0.80 | PGR (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL16162334 | 0.79 | CES2 (0.53) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL13686376 | 0.79 | SMN1; SMN2 (0.53) | TDP1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6509115 | 0.78 | AKR1C3 (0.43) | ALDH1A1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867310-B1 | Arylation and vinylation of activated carbons | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-03-15 | — | — | US | disclosed |