Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349926 | 0.89 | VCAM1 (0.48) | ALDH1A1KMT2AVCAM1CA1CA2 | |
| SCHEMBL11681535 | 0.83 | VCAM1 (0.55) | ALDH1A1KMT2ATDP1VCAM1CCR6 | |
| SCHEMBL28325618 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KMT2ATDP1VCAM1CCR6 | |
| SCHEMBL7754095 | 0.82 | VCAM1 (0.50) | ALDH1A1TDP1VCAM1CA12CA1 | |
| SCHEMBL274368 | 0.81 | MCOLN3 (0.56) | ALDH1A1KMT2AMEN1POLBPKM | |
| SCHEMBL30430459 | 0.81 | MCOLN3 (0.56) | ALDH1A1KMT2AMEN1POLBPKM | |
| SCHEMBL7513754 | 0.80 | NSD2 (0.61) | ALDH1A1KMT2ATDP1VCAM1CCR6 | |
| SCHEMBL17431600 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2ATDP1VCAM1CCR6 | |
| SCHEMBL3929621 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2ATDP1VCAM1CCR6 | |
| SCHEMBL14502784 | 0.80 | CA2 (0.67) | ALDH1A1KMT2ATDP1VCAM1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211696-B2 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | THE OHIO STATE UNIVERSITY (US) | 2007-05-01 | — | — | US | disclosed |
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0288824-B1 | AROMATIC DIAMINES CONTAINING SULFONIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYURETHANE POLYMERS | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-4797427-A | ESTERIFICATION, HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0288824-A2 | Aromatic diamines containing sulfonic acid esters, process for their preparation and their use for the preparation of polyurethane polymers | BAYER AG (DE) | 1988-11-02 | — | — | EP | disclosed |
| US-4587275-A | AROMATIC DIAMINE WITH SULFONIC ACID GROUP AS CHAIN EXTENSION AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-06 | — | — | US | disclosed |
| EP-0037030-A1 | Aromatic diamines containing sulphon amide groups | BAYER AG (DE) | 1981-10-07 | — | — | EP | disclosed |
| US-4060549-A | Process for preparing sulfonic acid fluorides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |