SCHEMBL6519018

SCHEMBL6519018

Oc1cc(C(Cl)(Cl)Cl)ccc1S

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
ESR1 P03372 4/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520615 0.98 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL6516444 0.98 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL6520621 0.98 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL28826937 0.89 ALDH1A1 (0.39) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL9305500 0.73 ALOX15 (0.50) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL17696923 0.73 CA3 (0.50) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL6520293 0.73 TSHR (0.43) TSHRALDH1A1HPGDHSD17B10
SCHEMBL6512927 0.71 TSHR (0.41) TSHRALDH1A1HPGDHSD17B10
SCHEMBL6520775 0.71 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL6512922 0.71 TSHR (0.41) TSHRALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed