Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308489 | 0.82 | ALDH1A1 (0.63) | ALOX15HSD17B10GAAMEN1MAPT | |
| SCHEMBL3485065 | 0.78 | TSHR (0.48) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL29397448 | 0.77 | ESR1 (0.56) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL1024107 | 0.77 | MAPT (0.69) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL6823132 | 0.77 | ALDH1A1 (0.50) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL565076 | 0.77 | ESR1 (0.56) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL3947426 | 0.77 | HSD17B10 (0.50) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL1025296 | 0.77 | ALDH1A1 (0.50) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL29412591 | 0.77 | ESR1 (0.56) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL28826937 | 0.77 | ALDH1A1 (0.39) | ALOX15HSD17B10GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324808-A | Polybenzimidazoles, polybenzoazoles or polybenzothiazoles | THE DOW CHEMICAL COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| US-5235023-A | Forming polybenzimidazoles, polybenzthiazoles and polybenz-oxazoles; disodium or dilithium terephthalate monomer | THE DOW CHEMICAL COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0449811-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006960-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |