Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122576 | 1.00 | MAPT (0.69) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL5955341 | 1.00 | MAPT (0.69) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL6013980 | 0.98 | PKM (0.71) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL8631891 | 0.98 | MAPT (0.67) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL8134887 | 0.98 | MAPT (0.67) | MAPTPKMALDH1A1HTTPOLB | |
| Hydrochloric Acid SCHEMBL3244036 | 0.98 | ALDH1A1 (0.67) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL3977980 | 0.98 | PKM (0.71) | MAPTPKMALDH1A1HTTPOLB | |
| SCHEMBL3419433 | 0.98 | MAPT (0.67) | MAPTPKMALDH1A1HTTPOLB | |
| Bromide SCHEMBL3967182 | 0.96 | MAPT (0.65) | MAPTPKMALDH1A1HTTPOLB | |
| Bromide SCHEMBL3970603 | 0.96 | PKM (0.69) | MAPTPKMALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117169393-A | Method for detecting cyclic peptide in plant tissue | 杭州湃肽生化科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-115108999-B | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2023-11-03 | — | — | CN | claimed |
| CN-115108999-A | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2022-09-27 | — | — | CN | claimed |
| CN-114920704-A | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2022-08-19 | — | — | CN | claimed |
| CN-110283123-B | 4-p-toluenesulfonyl piperazine-3-nitro-1, 8-naphthalimide derivative and synthesis method and application thereof | 桂林医学院 | 2022-06-17 | — | — | CN | claimed |
| CN-110283123-A | 4- p-toluenesulfonyl piperazine -3- nitro -1,8- naphthalimide derivative and its synthetic method and application | 桂林医学院 | 2019-09-27 | — | — | CN | claimed |
| WO-2006014405-A2 | SULFONAMIDE-BASED COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-02-09 | — | — | WO | claimed |
| US-20060004197-A1 | Sulfonamide-based compounds as protein tyrosine kinase inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-01-05 | — | — | US | claimed |
| US-4087425-A | N,N-Disulfonylpiperazines | LABORATORIOS LIADE, S.A. (ES) | 1978-05-02 | — | — | US | claimed |
| US-20250276069-A1 | HETEROBIFUNCTIONAL COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION AND METHODS FOR THEIR USE | THE SCRIPPS RESEARCH INSTITUTE | 2025-09-04 | — | — | US | disclosed |
| WO-2025137146-A1 | SUBSTITUTED HETEROARYL ANALOGS AND USES THEREOF FOR THE TREATMENT OF HIV-ASSOCIATED NEUROCOGNITIVE DISORDERS | MOUKHA CHAFIQ OMAR (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-120025295-A | Difluoromethyl and amino substituted olefin compound and synthesis method thereof | 浙江师范大学 | 2025-05-23 | — | — | CN | disclosed |
| CN-119798161-A | Preparation method of plant growth regulating substance and multiple uses thereof | 贵州工业职业技术学院 | 2025-04-11 | — | — | CN | disclosed |
| CN-119409667-A | Dithioacetal derivative containing sulfonyl piperazine unit, and preparation method and application thereof | 贵州大学 | 2025-02-11 | — | — | CN | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |
| EP-0567126-A1 | Processing composition for silver halide photographic material and processing method using same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-5147765-A | Desilvering; stability, discoloration inhibition | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0427204-A1 | Method for processing silver halide colour photographic materials | Fuji Photo Film Co., Ltd. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-3943135-A | ANTHELMINTIC | SANRAKU-OCEAN CO., LTD. (JA) | 1976-03-09 | — | — | US | disclosed |
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004197-A1 | Sulfonamide-based compounds as protein tyrosine kinase inhibitors | SRC, LCK, ABL1 | MAPT 1090/4885PKM 2383/4885ALDH1A1 4728/4885 |
| US-20250276069-A1 | HETEROBIFUNCTIONAL COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION AND METHODS FOR THEIR USE | USP28, PSMB11, PSMB1 | MAPT 2732/4885PKM 3436/4885ALDH1A1 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.