SCHEMBL6519640

SCHEMBL6519640

C[C@H](NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
HPGDS O60760 1/20 0.62
DGAT1 O75907 1/20 0.60
CA2 P00918 2/20 0.59
CA1 P00915 1/20 0.59
ALDH1A1 P00352 2/20 0.58
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
ALOX12 P18054 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
ROCK2 O75116 1/20 0.55
RPS6KA5 O75582 1/20 0.55
MAP4K4 O95819 1/20 0.55
CDK1 P06493 1/20 0.55
CSF1R P07333 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652059 1.00 NPC1 (0.62) NPC1RAB9AHPGDSDGAT1CA2
SCHEMBL1750579 1.00 NPC1 (0.62) NPC1RAB9AHPGDSDGAT1CA2
SCHEMBL2796740 0.89 CA1 (0.62) RAB9ADGAT1CA2CA1ALDH1A1
SCHEMBL698880 0.89 CA1 (0.62) RAB9ADGAT1CA2CA1ALDH1A1
SCHEMBL698879 0.89 CA1 (0.62) RAB9ADGAT1CA2CA1ALDH1A1
SCHEMBL11103451 0.89 CA2 (0.71) NPC1RAB9ADGAT1CA2CA1
SCHEMBL11103438 0.89 CA2 (0.71) NPC1RAB9ADGAT1CA2CA1
SCHEMBL4067128 0.85 ALDH1A1 (0.71) NPC1RAB9AHPGDSALDH1A1LMNA
SCHEMBL25554375 0.85 HDAC8 (0.60) ALDH1A1MME
SCHEMBL25554182 0.85 HDAC8 (0.60) ALDH1A1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L-Base Co., Ltd. (KR) 2023-05-25 US disclosed
US-20050124535-A1 Cyclic peptide nanotube structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE 2005-06-09 US disclosed
US-6902720-B2 Cyclic peptide structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE (US) 2005-06-07 US disclosed
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124535-A1 Cyclic peptide nanotube structures for molecular scale electronic and photonic devices NPPA, NGF, QRFPR NPC1 3127/4885RAB9A 713/4885HPGDS 4127/4885
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER VIP, QPCT, TPT1 NPC1 1243/4885RAB9A 2593/4885HPGDS 158/4885
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices VIP, NPPA, NGLY1 NPC1 3048/4885RAB9A 3454/4885HPGDS 3380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.