SCHEMBL652053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5350269	0.78	TTBK1 (0.45)	POLBMAPTSMN1; SMN2EGFRKDR
	SCHEMBL5785011	0.76	EGFR (0.54)	EGFRERBB2
	Hydrochloric Acid SCHEMBL5350968	0.76	EGFR (0.53)	EGFRERBB2
	Hydrochloric Acid SCHEMBL5351366	0.76	EGFR (0.53)	EGFRERBB2
	SCHEMBL652979	0.74	NPC1 (0.44)	POLBMAPTSMN1; SMN2
	SCHEMBL5356576	0.72	GSK3B (0.56)	EGFRABCG2
	SCHEMBL5358394	0.72	EGFR (0.56)	EGFRABCG2
	SCHEMBL5353750	0.71	EGFR (0.55)	EGFRERBB2
	SCHEMBL4913022	0.71	EGFR (0.56)	EGFRERBB2KDRGRM1MAPK1
	SCHEMBL5352136	0.71	TTBK1 (0.45)	KDRABCG2FLT4AURKBRPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.