SCHEMBL6520866

SCHEMBL6520866

O=S(=O)(F)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.48
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TRPV4 Q9HBA0 4/20 0.39
GAA P10253 1/20 0.36
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA6 P23280 3/20 0.34
CA9 Q16790 3/20 0.34
CA4 P22748 2/20 0.34
CA12 O43570 2/20 0.34
CYP2C9 P11712 2/20 0.34
CA5A P35218 2/20 0.34
CA7 P43166 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
FAAH O00519 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRTN3 P24158 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10381875 0.87 ELANE (0.58) ELANEALDH1A1HSD17B10TDP1GAA
SCHEMBL29985855 0.87 ELANE (0.58) ELANEALDH1A1HSD17B10TDP1GAA
SCHEMBL250199 0.87 ALDH1A1 (0.55) ELANEALDH1A1HSD17B10TDP1TRPV4
SCHEMBL10415459 0.79 GAA (0.50) ALDH1A1HSD17B10TDP1TRPV4GAA
SCHEMBL30690139 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1TRPV4GAA
SCHEMBL9360977 0.75 TDP1 (0.44) ALDH1A1HSD17B10TDP1TRPV4GAA
SCHEMBL9827202 0.75 CA2 (0.56) ALDH1A1HSD17B10TDP1GAACA1
SCHEMBL30605911 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1KMT2A
SCHEMBL16412 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1KMT2A
SCHEMBL489571 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1TRPV4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476515-A Removing natural lens from capsular sac, injecting modified collagen composition to fill sac, exposing to polymerization agent to polymerize and form intraocular lens AUTOGENESIS TECHNOLOGIES, INC. (US) 1995-12-19 US claimed
WO-1993002639-A1 INJECTABLE COLLAGEN-BASED COMPOSITIONS FOR MAKING INTRAOCULAR LENS AUTOGENESIS TECHNOLOGIES, INC. (US) 1993-02-18 WO claimed
EP-4337258-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2024-03-20 EP disclosed
US-20220362438-A1 Derivatized or Rapidly Polymerizing Collagen Compositions for Tissue Augmentation Containing Nonresorbable or Slowly Resorbable Polymers SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2022-11-17 US disclosed
WO-2022237900-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2022-11-17 WO disclosed
EP-1051655-B1 METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY ISTA PHARMACEUTICALS INC (US) 2005-09-28 EP disclosed
US-20010016731-A1 Methods and apparatus for accelerated orthokeratology DEVORE DALE (US) 2001-08-23 US disclosed
US-6204365-B1 Collagen modulators for use in photoablation eximer laser keratectomy COLLAGENESIS, INC. 2001-03-20 US disclosed
US-6161544-A Methods for accelerated orthokeratology KERATOFORM, INC. (US) 2000-12-19 US disclosed
US-5861486-A Collagen modulators for use in photoablation eximer laser keratectomy EUCLID SYSTEMS CORPORATION 1999-01-19 US disclosed
US-5492135-A Collagen modulators for use in photoablation excimer laser keratectomy COLLAGEN MATRIX TECHNOLOGIES, INC. 1996-02-20 US disclosed
US-4786316-A PRE-AND POST-EMERGENT HERBICIDES, PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
US-4652304-A Herbicidal ortho-sulfamoyl sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-24 US disclosed
EP-0164017-A2 Substituted phenyl sulfonyl ureas BAYER AG (DE) 1985-12-11 EP disclosed
EP-0160219-A1 Substituted sulphonyl ureas BAYER AG (DE) 1985-11-06 EP disclosed
US-4533626-A Photographic light-sensitive material with 4-(paranitrophenylazo)naphthol dyes FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
EP-0135332-A1 Herbicidal benzenesulfonamides, benzylsulfonamides and benzenesulfamates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-03-27 EP disclosed
US-4235813-A INTERMEDIATE IN PREPARATION OF CYAN DYE-RELEASING REDOX COMPOUNDS FOR DIFFUSION TRANSFER PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1980-11-25 US disclosed
US-4176134-A A CHEMICAL INTERMEDIATE FOR CYAN-DYE RELEASING REDOX COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1979-11-27 US disclosed
US-3935117-A Photosensitive etching composition FUJI PHOTO FILM CO., LTD. (JA) 1976-01-27 US disclosed