SCHEMBL6520872

SCHEMBL6520872

C=C(C(=O)O)C(CC)(CC(=O)C(C)c1ccccc1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 1/20 0.33
RIPK1 Q13546 1/20 0.33
PABPC1 P11940 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6522175 0.80 HCAR2 (0.40) MAPT
SCHEMBL6523748 0.78 CYP2D6 (0.36) PTGS2MEN1KMT2AHPGDFAAH
SCHEMBL6517405 0.77 POLB (0.40) MAPTMEN1KMT2AHPGD
SCHEMBL6523988 0.74 KIF11 (0.35) MAPTMEN1KMT2AHPGD
SCHEMBL9355502 0.73 SMN1; SMN2 (0.44) RIPK1
SCHEMBL6513813 0.72 HCAR2 (0.42) MAPTHPGD
SCHEMBL24086643 0.72 RIPK1 (0.44) PTGS2MAPTMEN1KMT2AHPGD
SCHEMBL676152 0.71 TET2 (0.37) MEN1KMT2A
SCHEMBL6515160 0.70 TET2 (0.35)
SCHEMBL6516106 0.70 TET2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 PTGS2 2336/4885MAPT 3438/4885MEN1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.