SCHEMBL6521976

SCHEMBL6521976

CCc1ccc2c(=O)c3ccccc3oc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
GLA P06280 1/20 0.60
CYP3A4 P08684 1/20 0.60
MAPT P10636 1/20 0.60
HPGD P15428 1/20 0.60
PGAM1 P18669 1/20 0.60
CASP1 P29466 1/20 0.60
CASP7 P55210 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HSD17B10 Q99714 1/20 0.60
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
CYP19A1 P11511 1/20 0.56
CYP11B1 P15538 1/20 0.56
CYP11B2 P19099 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
TTR P02766 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3091546 0.90 MAOA (0.60) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30999865 0.90 MAOA (0.60) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30810814 0.90 AHR (0.53) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL10306815 0.90 AHR (0.53) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL10884700 0.88 HTR1A (0.48) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL18798555 0.88 NPC1 (0.62) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL18242719 0.87 MAOA (0.56) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL18242248 0.84 MAOA (0.53) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL9851917 0.83 KIF11 (0.44) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL8711547 0.83 MAOA (0.60) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-9637565-B2 Photoinitiating system for anionic polymerization UVIC INDUSTRY PARTNERSHIPS INC. (US) 2017-05-02 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
US-20050028895-A1 Radiation curable precious metal preparation, transfers containing same and method for decoration FERRO GMBH (DE) 2005-02-10 US disclosed
EP-1291335-B1 Radiation curable precious metal composition, decalcomanias containing it and method of decorating FERRO GMBH (DE) 2004-08-11 EP disclosed
WO-2003022781-A1 RADIATION CURABLE PRECIOUS METAL PREPARATION, TRANSFERS CONTAINING SAME AND METHOD FOR DECORATION FERRO GMBH (DE) 2003-03-20 WO disclosed
EP-1291335-A1 Radiation curable precious metal composition, decalcomanias containing it and method of decorating OMG AG & Co. KG (DE) 2003-03-12 EP disclosed
US-4379039-A Ultraviolet curable resin composition TOYO BOSEKI KABUSHIKI KAISH (JP) 1983-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 MAOA 403/4885KDM4E 4342/4885ALDH1A1 151/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 MAOA 403/4885KDM4E 4342/4885ALDH1A1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.