Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522088 | 0.83 | NPSR1 (0.36) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL1327582 | 0.81 | NPSR1 (0.36) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL6518505 | 0.80 | C5AR1 (0.37) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL1328717 | 0.79 | C5AR1 (0.37) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL1328707 | 0.78 | NPSR1 (0.38) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL6515324 | 0.77 | MAPT (0.41) | MAPTNPSR1L3MBTL1 | |
| SCHEMBL6520800 | 0.76 | ALOX5 (0.43) | C5AR1 | |
| SCHEMBL1328160 | 0.76 | C5AR1 (0.41) | C5AR1MAPTNPSR1L3MBTL1 | |
| SCHEMBL6522026 | 0.75 | S1PR1 (0.41) | C5AR1 | |
| SCHEMBL6522043 | 0.74 | PPARA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565452-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004043925-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |