SCHEMBL6523938

SCHEMBL6523938

Cc1ccc(OC(=O)/C=C/C(=O)OCC(=O)Cc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 4/20 0.47
KMT2A Q03164 3/20 0.47
HCAR2 Q8TDS4 2/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
GAA P10253 3/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 3/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
MDM4 O15151 1/20 0.40
MDM2 Q00987 1/20 0.40
EPHX2 P34913 1/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520905 0.90 HCAR2 (0.49) L3MBTL1MAPTKMT2AHCAR2GAA
SCHEMBL6516502 0.81 MAPT (0.52) L3MBTL1MAPTKMT2AHCAR2MEN1
SCHEMBL6514405 0.81 NPC1 (0.60) TDP1L3MBTL1MAPTKMT2AMEN1
SCHEMBL6516612 0.78 LMNA (0.52) TDP1L3MBTL1MAPTKMT2AGAA
SCHEMBL6516054 0.78 NPC1 (0.60) TDP1L3MBTL1MAPTKMT2AMEN1
SCHEMBL6523619 0.78 HCAR2 (0.54) TDP1MAPTKMT2AHCAR2MEN1
SCHEMBL789755 0.78 SMN1; SMN2 (0.60) TDP1L3MBTL1KMT2ACNR1CNR2
SCHEMBL6518196 0.77 KMT2A (0.46) TDP1L3MBTL1KMT2ACNR1CNR2
SCHEMBL8998922 0.75 LMNA (0.64) TDP1L3MBTL1KMT2AGAAMEN1
SCHEMBL8998925 0.75 LMNA (0.64) TDP1L3MBTL1KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 TDP1 1789/4885L3MBTL1 1615/4885MAPT 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.