SCHEMBL6523619

SCHEMBL6523619

COCCOC(=O)/C=C/C(=O)OCC(=O)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.54
AKR1B10 O60218 6/20 0.48
AKR1B1 P15121 6/20 0.48
MAPT P10636 2/20 0.46
ALOX5 P09917 5/20 0.44
TTR P02766 4/20 0.44
TSHR P16473 2/20 0.44
MAOB P27338 1/20 0.44
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
GMNN O75496 1/20 0.41
ALDH1A1 P00352 1/20 0.41
EGFR P00533 1/20 0.41
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6516502 0.87 MAPT (0.52) HCAR2AKR1B10AKR1B1MAPTMAPK1
SCHEMBL6520905 0.81 HCAR2 (0.49) HCAR2AKR1B10AKR1B1MAPTMAOB
SCHEMBL6525924 0.79 KMT2A (0.56) HCAR2AKR1B10AKR1B1MAPTTSHR
SCHEMBL6520752 0.78 HCAR2 (0.68) HCAR2AKR1B10AKR1B1MAPTALOX5
SCHEMBL6523938 0.78 TDP1 (0.48) HCAR2MAPTMEN1ALDH1A1LMNA
SCHEMBL3628816 0.76 CES1 (0.52) AKR1B1MAPTTSHRMAPK1KDM4E
SCHEMBL6523964 0.75 TDP1 (0.40) MAPTALOX5TSHRMAPK1KDM4E
SCHEMBL9736831 0.75 ALDH1A1 (0.61) AKR1B1MAPTALOX5TSHRMAPK1
SCHEMBL6516717 0.75 ATM (0.47) HCAR2MAPTALOX5TSHRHPGD
SCHEMBL9860306 0.74 HCAR2 (0.89) HCAR2AKR1B10AKR1B1MAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 HCAR2 3143/4885AKR1B10 2430/4885AKR1B1 2731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.