SCHEMBL652529

SCHEMBL652529

CC(C)C1C=Cc2nc3ccccc3nc2C1=O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.39
▸ RAB9A P51151 4/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ AHR P35869 1/20 0.39
▸ ELANE P08246 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ MCOLN3 Q8TDD5 1/20 0.31
▸ TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2928380 0.79 MAPT (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL27592760 0.76 MAPT (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL31450545 0.76 MAPT (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL2501720 0.76 MAPT (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL387792 0.76 MAPT (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL10983158 0.76 NPC1 (0.38) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL6669049 0.75 MAPT (0.35) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL28361348 0.75 ALDH1A1 (0.37) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL6889912 0.73 MAPT (0.36) MAPTRAB9AALDH1A1SMN1; SMN2NPC1
Sulfuric Acid SCHEMBL6839880 0.73 RAB9A (0.37) MAPTRAB9AALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102351794-A Refined recovery process of isopropylantipyrine recycling product SHANDONG XINHUA PHARMACEUTICAL 2012-02-15 — — CN claimed
CN-1300208-A Icecream-type pharmaceutical formulation and process for preparing the same MOGAM BIOTECH RES INST (KR) 2001-06-20 — — CN claimed
EP-2094210-B2 MEDICAL FABRIC HARTMANN PAUL AG (DE) 2021-09-08 — — EP disclosed
WO-2021074080-A1 KIT COMPOSED OF A TWO-PART TISSUE ADHESIVE AND A TEMPORARY PROTECTIVE LINER THEREFOR, AND USE THEREOF ADHESYS MEDICAL GMBH (DE) 2021-04-22 — — WO disclosed
EP-3786207-A1 ISOCYANATE FUNCTIONAL PRE-POLYMER FOR A BIODEGRADABLE TISSUE ADHESIVE Adhesys Medical GmbH (DE) 2021-03-03 — — EP disclosed
EP-3385294-B1 ISOCYANATE FUNCTIONAL PRE-POLYMER FOR A BIODEGRADABLE TISSUE ADHESIVE ADHESYS MEDICAL GMBH (DE) 2020-11-11 — — EP disclosed
CN-111650307-A Method for simultaneously qualitatively and quantitatively detecting illegal additives of antipyretic and analgesic drugs in wine and application 重庆医药高等专科学校 2020-09-11 — — CN disclosed
WO-2019145926-A1 STABLE THIAMINE CONTAINING PHARMACEUTICAL FORMULATIONS FORTUNE PHARMACAL COMPANY LIMITED (CN) 2019-08-01 — — WO disclosed
EP-2760901-B1 ALPHA-ALKOXYSILANE-TERMINATED PREPOLYMER FOR QUICK HARDENING SPRAY FOAMS WITH IMPROVED FUEL GAS SOLUBILITY COVESTRO DEUTSCHLAND AG (DE) 2018-12-05 — — EP disclosed
EP-3385294-A1 ISOCYANATE FUNCTIONAL PRE-POLYMER FOR A BIODEGRADABLE TISSUE ADHESIVE Adhesys Medical GmbH (DE) 2018-10-10 — — EP disclosed
EP-2094210-B1 MEDICAL FABRIC HARTMANN PAUL AG (DE) 2018-06-20 — — EP disclosed
WO-2011098444-A1 ACTIVE SUBSTANCE-RELEASING WOUND DRESSING BAYER MATERIALSCIENCE AG (DE) 2011-08-18 — — WO disclosed
EP-2094210-A2 MEDICAL FABRIC Paul Hartmann AG (DE) 2009-09-02 — — EP disclosed
CN-101426808-A Novel protein transduction domains and uses thereof UNIV ARIZONA (US) 2009-05-06 — — CN disclosed
CN-101328147-A Low-voltage hydrogenation process of isopropyl pyrazolone SHANDONG XINHUA PHARMACEUTICAL (CN) 2008-12-24 — — CN disclosed
US-20080249486-A1 Medicinal Composition with Active Ingredients and Wound Contact Layer with a Composition PAUL HARTMANN AG (DE) 2008-10-09 — — US disclosed
EP-1962802-A1 MEDICINAL COMPOSITION WITH ACTIVE INGREDIENTS AND WOUND CONTACT LAYER WITH A COMPOSITION Paul Hartmann AG (DE) 2008-09-03 — — EP disclosed
WO-2008080532-A2 MEDICAL FABRIC PAUL HARTMANN AG (DE) 2008-07-10 — — WO disclosed
WO-2007068492-A1 MEDICINAL COMPOSITION WITH ACTIVE INGREDIENTS AND WOUND CONTACT LAYER WITH A COMPOSITION PAUL HARTMANN AG (DE) 2007-06-21 — — WO disclosed
US-4192868-A ANTIINFLAMMATORY, ANALGESIC CIBA-GEIGY CORPORATION (US) 1980-03-11 — — US disclosed
Send feedback