Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928380 | 0.79 | MAPT (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL2501720 | 0.76 | MAPT (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL31450545 | 0.76 | MAPT (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL27592760 | 0.76 | MAPT (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL10983158 | 0.76 | NPC1 (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL387792 | 0.76 | MAPT (0.38) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL652529 | 0.75 | MAPT (0.39) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL28361348 | 0.75 | ALDH1A1 (0.37) | MAPTALDH1A1NPC1AHRRAB9A | |
| SCHEMBL6889912 | 0.73 | MAPT (0.36) | MAPTALDH1A1NPC1AHRRAB9A | |
| Sulfuric Acid SCHEMBL6839880 | 0.73 | RAB9A (0.37) | MAPTALDH1A1NPC1AHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453485-A2 | MATRICES FOR STABILIZING AND CONTROLLED RELEASE OF PROBLEMATIC SUBSTANCES | Göpferich, Achim, Prof. Dr. (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003049719-A2 | MATRICES FOR STABILIZING AND CONTROLLED RELEASE OF PROBLEMATIC SUBSTANCES | GOEPFERICH ACHIM (DE) | 2003-06-19 | — | — | WO | disclosed |