SCHEMBL387792

SCHEMBL387792

NC1C=Cc2nc3ccccc3nc2C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.38
▸ NPC1 O15118 6/20 0.38
▸ RAB9A P51151 5/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ AHR P35869 1/20 0.38
▸ CCNB2 O95067 1/20 0.35
▸ CDK1 P06493 1/20 0.35
▸ CCNB1 P14635 1/20 0.35
▸ CCNB3 Q8WWL7 1/20 0.35
▸ KDM4E B2RXH2 5/20 0.33
▸ MEN1 O00255 4/20 0.33
▸ KMT2A Q03164 4/20 0.33
▸ HPGD P15428 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ GAA P10253 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL7585957 0.91 MEN1 (0.41) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
Maleic Acid SCHEMBL28982547 0.89 HSD17B10 (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL27592760 0.79 MAPT (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL10983158 0.79 NPC1 (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL2928380 0.79 MAPT (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL2501720 0.79 MAPT (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL31450545 0.79 MAPT (0.38) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
Caffeine SCHEMBL27612824 0.77 ADORA2B (0.51) ALDH1A1SMN1; SMN2KDM4EKMT2APOLB
SCHEMBL6889912 0.77 MAPT (0.36) MAPTNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL652529 0.76 MAPT (0.39) MAPTNPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1840 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 — — US claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 — — US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 — — WO claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 — — US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 — — EP claimed
CN-119212681-A Method for preparing 3-D printed pharmaceutical products 百时美施贵宝公司 2024-12-27 — — CN claimed
US-20240269115-A1 PYRAZOLONE COMPOUNDS FOR USE IN DEGENERATIVE RETINAL DISEASES FLONEXT S.R.L. (IT) 2024-08-15 — — US claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 — — US claimed
WO-2024105529-A1 CHEMICAL DISBUDDING OF LIVESTOCK MASSEY UNIVERSITY (NZ) 2024-05-23 — — WO claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 — — EP claimed
CN-1245686-A Compound Niuduning oral liquor and its preparation method SHI DENG (CN) 2000-03-01 — — CN claimed
CN-1243723-A Quick-acting analgesic ointment LU ZIJUN (CN) 2000-02-09 — — CN claimed
WO-1998052616-A2 NONSTEROIDAL ANTIRHEUMATIC AGENTS OR THROMBOCYTE-AGGLUTINATION INHIBITORS TO IMPROVE REPRESENTATION OF VESSELS, LYMPH NODES AND BONE MARROW WITH PHARMACEUTICAL PREPARATIONS CONTAINING PARTICLES, VESICLES OF POLYMERS Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) 1998-11-26 — — WO claimed
CN-1156961-A Formulations and method for providing prolonged local anesthesia EURO CELTIQUE SA (LU) 1997-08-13 — — CN claimed
CN-1025474-C Medicine stick therapeutic equipment XUZHOU HEAVY DUTY MACHINERY PL (CN) 1994-07-20 — — CN claimed
US-5206006-A Peroxidase enzyme; phenylpyrazone derivative phenol or aromatic amine; stabilizer; storage discoloration inhibition INSTRUMENTATION LABORATORY SPA (IT) 1993-04-27 — — US claimed
EP-0408496-A2 Solid dosage form for pharmaceutical substances CIBA-GEIGY AG (CH) 1991-01-16 — — EP claimed
CN-1037833-A Medicine-stick therapeutic appliance and cooperating medicinal liquor XUZHOU HEAVY MACHINERY PLANT (CN) 1989-12-13 — — CN claimed
EP-0036145-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1985-05-29 — — EP claimed
EP-0007572-A1 Pharmaceutical mixtures containing an amantadine compound CIBA-GEIGY AG (CH) 1980-02-06 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240269115-A1 PYRAZOLONE COMPOUNDS FOR USE IN DEGENERATIVE RETINAL DISEASES ALDH1A2, PDK3, EYA3 MAPT 734/4885NPC1 654/4885RAB9A 2369/4885
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ASAH2, ASAH1, GBA2 MAPT 4462/4885NPC1 155/4885RAB9A 415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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