SCHEMBL6525842

SCHEMBL6525842

Cc1cccc(C(=O)COC(=O)/C=C/C(=O)OCc2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.55
LMNA P02545 1/20 0.49
GPR52 Q9Y2T5 1/20 0.48
AKR1B10 O60218 2/20 0.46
AKR1B1 P15121 2/20 0.46
CA12 O43570 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
MAPT P10636 2/20 0.45
TTR P02766 1/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6517490 0.86 HCAR2 (0.68) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL6518813 0.86 KMT2A (0.47) LMNAGPR52MAPTKMT2ANPC1
SCHEMBL6514319 0.85 KMT2A (0.62) HCAR2LMNAGPR52AKR1B10AKR1B1
SCHEMBL6519835 0.84 CTNNB1 (0.48) LMNAMAPTKMT2ANPC1RAB9A
SCHEMBL6516413 0.82 LMNA (0.49) LMNAMAPTKMT2ANPC1TDP1
SCHEMBL6514724 0.81 CTNNB1 (0.45) GPR52MAPTKMT2ANPC1RAB9A
SCHEMBL6057244 0.78 TDP1 (0.69) LMNAMAPTKMT2ANPC1RAB9A
SCHEMBL31137861 0.78 TDP1 (0.69) LMNAMAPTKMT2ANPC1RAB9A
SCHEMBL6514663 0.77 SMN1; SMN2 (0.46) LMNAMAPTKMT2ANPC1RAB9A
SCHEMBL337504 0.77 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 HCAR2 3143/4885LMNA 2459/4885GPR52 2240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.