SCHEMBL6519835

SCHEMBL6519835

COC(=O)/C=C/C(=O)OCC(=O)c1cccc(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.48
WNT3A P56704 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
GAA P10253 1/20 0.43
PARP1 P09874 2/20 0.43
PARP15 Q460N3 1/20 0.43
PARP14 Q460N5 1/20 0.43
PARP10 Q53GL7 1/20 0.43
MAPT P10636 6/20 0.43
ALDH1A1 P00352 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514724 0.88 CTNNB1 (0.45) CTNNB1WNT3AMEN1KMT2AHDAC8
SCHEMBL6516413 0.86 LMNA (0.49) CTNNB1WNT3AMEN1KMT2AGAA
SCHEMBL6518813 0.85 KMT2A (0.47) CTNNB1WNT3AMEN1KMT2ASMN1; SMN2
SCHEMBL6525842 0.84 HCAR2 (0.55) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL6516704 0.83 KMT2A (0.59) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL6523183 0.81 NPC1 (0.42) CTNNB1WNT3AMEN1KMT2AMAPT
SCHEMBL7171129 0.80 GPR52 (0.51) MEN1KMT2AHDAC8HDAC6SMN1; SMN2
SCHEMBL7568121 0.80 GPR52 (0.51) MEN1KMT2AHDAC8HDAC6SMN1; SMN2
SCHEMBL1210113 0.78 CTNNB1 (0.58) CTNNB1WNT3AMEN1KMT2AHDAC8
SCHEMBL31309786 0.78 CTNNB1 (0.58) CTNNB1WNT3AMEN1KMT2AHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 CTNNB1 2762/4885WNT3A 3766/4885MEN1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.