Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699527 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRHSD17B10POLB | |
| SCHEMBL5699504 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRHSD17B10POLB | |
| SCHEMBL3043061 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ATMMAPK1L3MBTL1KDM4E | |
| SCHEMBL338399 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ATMMAPK1L3MBTL1KDM4E | |
| SCHEMBL28404131 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ATMMAPK1L3MBTL1TSHR | |
| SCHEMBL28412717 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ATMMAPK1L3MBTL1TSHR | |
| SCHEMBL1169314 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ATMMAPK1L3MBTL1TSHR | |
| Ethylene SCHEMBL15653960 | 0.75 | ALDH1A1 (0.45) | ALDH1A1ATMMAPK1L3MBTL1KDM4E | |
| SCHEMBL1829443 | 0.73 | TSHR (0.40) | ALDH1A1MAPK1L3MBTL1TSHRHSD17B10 | |
| SCHEMBL17581863 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ATMMAPK1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884897-B2 | Preparation of 3,6-dihydro-2H-pyran-2-carboxylic esters | BAYER AKTIENGESELLSCHAFT (DE) | 2005-04-26 | — | — | US | disclosed |
| US-20030158430-A1 | Preparation of 3,6-dihydro-2H-pyran-2-carboxylic esters | LANXESS DEUTSCHLAND GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158430-A1 | Preparation of 3,6-dihydro-2H-pyran-2-carboxylic esters | GRHPR, GLO1, HPD | ALDH1A1 339/4885ATM 4865/4885MAPK1 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.