Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512656 | 0.81 | CYP1A2 (0.44) | SMN1; SMN2MEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6508760 | 0.78 | CA12 (0.45) | ARSMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL6508357 | 0.77 | IDO1 (0.31) | — | |
| SCHEMBL6512004 | 0.77 | NOTUM (0.46) | NOTUMARPTGS2SMN1; SMN2MEN1 | |
| SCHEMBL6509504 | 0.77 | NOTUM (0.51) | NOTUMARCYP2D6CYP2C19 | |
| SCHEMBL6507723 | 0.73 | DRD2 (0.42) | NOTUM | |
| SCHEMBL8103236 | 0.69 | NOTUM (0.43) | NOTUMAR | |
| SCHEMBL4085823 | 0.68 | AR (0.48) | NOTUMARSMN1; SMN2TSHR | |
| SCHEMBL4085825 | 0.68 | AR (0.48) | NOTUMARSMN1; SMN2TSHR | |
| SCHEMBL8098716 | 0.68 | NOTUM (0.45) | NOTUMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |