Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885582 | 0.87 | DRD2 (0.42) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL6508236 | 0.85 | ROCK2 (0.38) | HCRTR1HCRTR2ROCK2 | |
| SCHEMBL6508760 | 0.82 | CA12 (0.45) | DRD2DRD3 | |
| SCHEMBL9267232 | 0.82 | LIPE (0.46) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8556361 | 0.81 | DRD2 (0.44) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8556168 | 0.81 | DRD2 (0.44) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8093681 | 0.81 | NOTUM (0.45) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8554346 | 0.80 | MCHR1 (0.40) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8662936 | 0.80 | MCHR1 (0.40) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8662266 | 0.79 | MCHR1 (0.40) | DRD2DRD3KCNH2NOTUMMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |
| US-5688962-A | Cyclization process for making oxazolikinones | ZENECA LIMITED (GB) | 1997-11-18 | — | — | US | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |