Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508357 | 0.85 | IDO1 (0.31) | — | |
| SCHEMBL6527741 | 0.81 | NOTUM (0.45) | CYP1A2CYP2D6CYP2C19KMT2AMEN1 | |
| SCHEMBL7819041 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19KAT2BPIN1 | |
| SCHEMBL6530315 | 0.75 | CYP2D6 (0.50) | CYP1A2CYP2D6CYP2C19KMT2AMEN1 | |
| SCHEMBL6510492 | 0.75 | KAT2B (0.46) | CYP1A2CYP2D6CYP2C19KAT2BPIN1 | |
| SCHEMBL6508760 | 0.73 | CA12 (0.45) | CYP1A2KMT2AMEN1GAADRD2 | |
| SCHEMBL6508236 | 0.71 | ROCK2 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL13116279 | 0.68 | CYP2D6 (0.52) | CYP1A2CYP2D6CYP2C19KMT2AMEN1 | |
| SCHEMBL8554615 | 0.67 | SLC6A2 (0.47) | CYP1A2CYP2D6CYP2C19KAT2BPIN1 | |
| SCHEMBL8554739 | 0.67 | DRD2 (0.45) | CYP1A2CYP2D6CYP2C19KAT2BPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |