Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622294 | 0.76 | NOS3 (0.50) | NOS3NOS2NOS1ALDH1A1MAPT | |
| SCHEMBL6530965 | 0.75 | CCR1 (0.52) | NOS3NOS2 | |
| SCHEMBL3084862 | 0.71 | NOS3 (0.55) | NOS3NOS2NOS1ALDH1A1 | |
| SCHEMBL29648194 | 0.71 | NOS3 (0.55) | NOS3NOS2NOS1ALDH1A1 | |
| SCHEMBL22854565 | 0.69 | NOS3 (0.52) | NOS3NOS2NOS1APAF1ALDH1A1 | |
| SCHEMBL8999497 | 0.68 | RXFP1 (0.42) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL6532311 | 0.67 | NPC1 (0.38) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL3848271 | 0.63 | KMT2A (0.53) | ALDH1A1MAPTHPGDMAPK1HTT | |
| SCHEMBL2213825 | 0.63 | ADORA3 (0.59) | MAPK1HTT | |
| SCHEMBL16481895 | 0.63 | L3MBTL1 (0.47) | NOS3NOS2NOS1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026139-A1 | NEMATICIDAL DIFLUOROALKENES | BAYER CROPSCIENCE AG (DE) | 2005-03-24 | — | — | WO | disclosed |